C18 Chromatography Silica Gel Powder
C18 reversed phase silica gel is widely used for separating and purifying peptides, antibiotics, and small natural molecules. It offers versatility for conventional chromatographic applications. The C18 AQ variant enhances retention and selectivity for polar compounds in 100% aqueous phases by controlling bonding density. Additionally, C18 Polar, with its amide polar functional groups, provides different selectivity for polar compounds compared to C18 AQ, while also being suitable for use in 100% aqueous phases. These characteristics make C18 silica gel a critical tool in various chromatographic processes.
Technical Specifications
C18
Items | C18 | C18 | C18 | C18 |
Bonded Phase | Octadecyl | Octadecyl | Octadecyl | Octadecyl |
Size | 8μm, 10μm | 15μm, 20 μm, 30μm, 50μm | 15μm, 20 μm, 30μm, 50μm | 15μm, 20 μm, 30μm, 50μm |
Pore Diameter, Å | 100 | 120 | 200 | 300 |
Carbon Loading, %≥ | 17 | 16 | 12 | 7 |
PH | 2-8 | 2-8 | 2-8 | 2-8 |
C18 AQ & C18 Polar
Items | C18 AQ | C18 Polar |
Bonded Phase | Octadecyl | Acylamino intercalated octadecyl |
Size | 3μm, 5μm, 10μm | 3μm, 5μm,10μm |
Pore Diameter, Å | 120 | 120 |
Carbon Loading, %≥ | 15 | 16 |
PH | 2-8 | 2-8 |
Applications
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C18: is widely used in conventional chromatography for the separation and purification of most peptides, antibiotics, and small natural product molecules.
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C18 AQ: enhances retention and selectivity for polar compounds with its controlled bonding density, allowing for 100% aqueous phases.
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C18 Polar: introduces amide polar functional groups, providing unique selectivity for polar compounds compared to C18AQ, also supporting 100% aqueous phases.
Packing
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Standard Packing: Net Weight 15Kg, 20Kg, 25Kg PP Bag, 25Kg Fiber/Iron Drum, 500Kg, 800Kg Container Bag (customization available)
Storage and Handling
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Store in a cool, dry place away from direct sunlight and moisture. Avoid contact with incompatible materials like strong acids and bases. Wear appropriate personal protective equipment when handling.
Customization
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The moisture content, packing, and size can be customized according to your specific requirements.