Bonded Silica Gel for Chromatography
Bonded silica gel is a critical component in chromatographic analysis, particularly in high-performance liquid chromatography (HPLC). It refers to silica particles that have been chemically modified with various functional groups, enhancing their separation capabilities. The base material, silica, is known for its high surface area and porosity, making it an excellent medium for adsorption processes. We can supply the C18, C8, C4, Phenyl, Amino, Cyano, Thiol and Diol boned silica gel for various chromatography applications.
Products We Supply
Characteristics: The general C18 is suitable for analysis and purification for alkaline compounds
Application:
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Separation and purification of most peptides, antibiotics, and small natural product molecules.
C18-AQ (Octadecyl)
Characteristics: Based on the general C18, has strong stability in high aqueous phases.
Application:
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Separation and purification of most peptides, antibiotics, and small natural product molecules.
Characteristic: Similar to C18 but with a shorter chain (8 carbons). It provides less retention for hydrophobic compounds compared to C18
Application:
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Useful for faster separations of moderately non-polar compounds.
Characteristic: With an even shorter chain (4 carbons), C4 is used for very hydrophobic molecules or proteins, offering shorter retention times.
Application:
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Suitable for the separation of biological samples.
Characteristics: Contains a phenyl group attached to the silica. It provides unique selectivity due to π-π interactions.
Application:
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Useful for aromatic compounds.
Characteristics: NH2 amino-bonded silica gel is a chromatographic packing material with high-purity silica gel as its substrate, onto which aminopropyl functional groups are bonded.
Application:
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Normal-phase and reverse-phase mode analysis
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HILIC (Hydrophilic Interaction Liquid Chromatography) mode analysis.
Characteristics: The cyano group can be used in both reversed-phase and normal-phase chromatography, offering intermediate polarity.
Application:
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In the normal-phase mode, it can replace silica gel, providing higher selectivity and faster equilibration compared to non-functionalized silica gel.
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In the reverse-phase mode, CN silica gel can replace C18 for certain special separations.
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Additionally, it has a strong rapid equilibration capability compared to bare silica gel, making it suitable for the separation and analysis of protein steroids, polar natural products, and more.
Characteristics: Silica modified with thiol groups can adsorb heavy metal ions efficiently, offering a simple and easy-to-operate method with significant adsorption effects.
Application:
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Specifically adsorb heavy metals, including Pd²⁺, Pb²⁺, Cu²⁺, Cd²⁺, Ni²⁺, and Co²⁺, with excellent adsorption performance and no secondary pollution.
Features diol groups, useful in normal-phase chromatography for separating polar compounds like carbohydrates.
Customization
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All the above products be customized according to your specific requirements.